Fabrication of Coated-Collagen Electrospun PHBV Nanofiber Film by Plasma Method and Its Cellular Study
Joint Authors
Heidari K, Saeed
Asefnejad, Azadeh
Pourshamsian, Khalil
Ejazi, Fahimeh
Montazeri, Mohamad
Ghorbani, Fatemeh
Biazar, Esmaeil
Ai, Jafar
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Civil Engineering
Abstract EN
Background.
Tissue engineering is defined as the designing and engineering of structures to rebuild and repair a body damaged tissue.
Scaffolding Poly Hydroxy Butyrate Valerate (PHBV) has shown good biocompatibility and biodegradable properties.
Nanofibers have improved the performance of biomaterials, and could be considered effective.
One of the important methods for designing nanofiber scaffold is the electrospinnig method.
In this study, PHBV nanofibers were well designed and then, modified with the immobilized collagen via the plasma method.
The samples were evaluated by ATR-FTIR, SEM, contact angle, and, finally, cell culture.
Results.
ATR-FTIR structural analysis showed the presence of collagen on the nanofiber surfaces.
The SEM images showed the size average of nanofibers as to be about 280 nm; that increased with a collagen coating up to 300 nm.
Contact angle analysis showed 67 degree for uncoated nanofibers and 56 degree for coated nanofibers.
Cellular investigations (USS cells) showed better adhesion and cell growth and proliferation of coated samples than uncoated samples.
Conclusions.
In this work, the PHBV nanofibers with a size average about 280 nm were designed.
Nanofibers were successfully coated with collagen via the plasma methods.
These collagen-coated nanofibers could be used well for tissue engineering.
American Psychological Association (APA)
Ai, Jafar& Heidari K, Saeed& Ghorbani, Fatemeh& Ejazi, Fahimeh& Biazar, Esmaeil& Asefnejad, Azadeh…[et al.]. 2011. Fabrication of Coated-Collagen Electrospun PHBV Nanofiber Film by Plasma Method and Its Cellular Study. Journal of Nanomaterials،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-447442
Modern Language Association (MLA)
Ai, Jafar…[et al.]. Fabrication of Coated-Collagen Electrospun PHBV Nanofiber Film by Plasma Method and Its Cellular Study. Journal of Nanomaterials No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-447442
American Medical Association (AMA)
Ai, Jafar& Heidari K, Saeed& Ghorbani, Fatemeh& Ejazi, Fahimeh& Biazar, Esmaeil& Asefnejad, Azadeh…[et al.]. Fabrication of Coated-Collagen Electrospun PHBV Nanofiber Film by Plasma Method and Its Cellular Study. Journal of Nanomaterials. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-447442
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447442