MicroRNA Expression in Selected Carcinomas of the Gastrointestinal Tract
Joint Authors
Panarelli, Nicole C.
Yantiss, Rhonda K.
Source
Pathology Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-13
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
MicroRNAs (miRNAs) comprise a recently discovered class of small, 18–25 nucleotide, noncoding RNA sequences that regulate gene expression at the posttranscriptional level by binding to and inhibiting the translation of target messenger RNAs (mRNAs).
Characteristic patterns of miRNA expression have been described in several malignancies of the gastrointestinal tract, and numerous investigators have demonstrated interactions between specific miRNA species and target oncogenes or tumor-suppressor genes.
It is clear that miRNAs play an important role in regulating expression of a number of genes involved in gastrointestinal carcinogenesis, and, thus, these molecules may represent either diagnostic markers of, or therapeutic targets for, some types of malignancy.
This paper summarizes the literature regarding miRNA expression in carcinomas of the colon, pancreas, and liver and discusses some of the mechanisms by which these molecules participate in gastrointestinal oncogenesis.
American Psychological Association (APA)
Panarelli, Nicole C.& Yantiss, Rhonda K.. 2011. MicroRNA Expression in Selected Carcinomas of the Gastrointestinal Tract. Pathology Research International،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-447511
Modern Language Association (MLA)
Panarelli, Nicole C.& Yantiss, Rhonda K.. MicroRNA Expression in Selected Carcinomas of the Gastrointestinal Tract. Pathology Research International No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-447511
American Medical Association (AMA)
Panarelli, Nicole C.& Yantiss, Rhonda K.. MicroRNA Expression in Selected Carcinomas of the Gastrointestinal Tract. Pathology Research International. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-447511
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447511