TLR2 and TLR4 in the Brain Injury Caused by Cerebral Ischemia and Reperfusion
Joint Authors
Zhu, Yuhong
Ge, Pengfei
Wang, Ying
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Brain injury caused by cerebral ischemia/reperfusion is a complicated pathophysiological course, in which inflammation is thought to play an important role.
Toll-like receptors are a type of transmembrane proteins, which can recognize either exogenous pathogen-associated molecular patterns or endogenous stress or damage-associated molecular patterns in the innate immune system and initiate inflammatory responses.
Among Toll-like receptors, TLR2 and TLR4 are found to be more important than others in the pathological progression of cerebral injury due to ischemia and reperfusion.
This review will focus on the biological characteristics and functions of TLR2 and TLR4 and their downstream signal pathways.
American Psychological Association (APA)
Wang, Ying& Ge, Pengfei& Zhu, Yuhong. 2013. TLR2 and TLR4 in the Brain Injury Caused by Cerebral Ischemia and Reperfusion. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-447514
Modern Language Association (MLA)
Wang, Ying…[et al.]. TLR2 and TLR4 in the Brain Injury Caused by Cerebral Ischemia and Reperfusion. Mediators of Inflammation No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-447514
American Medical Association (AMA)
Wang, Ying& Ge, Pengfei& Zhu, Yuhong. TLR2 and TLR4 in the Brain Injury Caused by Cerebral Ischemia and Reperfusion. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-447514
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447514