Stem Cell-Based Cell Therapy for Glomerulonephritis
Joint Authors
Chen, Xiangmei
Xie, Yuansheng
Jin, Meiling
Li, Qinggang
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-09
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Glomerulonephritis (GN), characterized by immune-mediated inflammatory changes in the glomerular, is a common cause of end stage renal disease.
Therapeutic options for glomerulonephritis applicable to all cases mainly include symptomatic treatment and strategies to delay progression.
In the attempt to yield innovative interventions fostering the limited capability of regeneration of renal tissue after injury and the uncontrolled pathological process by current treatments, stem cell-based therapy has emerged as novel therapy for its ability to inhibit inflammation and promote regeneration.
Many basic and clinical studies have been performed that support the ability of various stem cell populations to ameliorate glomerular injury and improve renal function.
However, there is a long way before putting stem cell-based therapy into clinical practice.
In the present article, we aim to review works performed with respect to the use of stem cell of different origins in GN, and to discuss the potential mechanism of therapeutic effect and the challenges for clinical application of stem cells.
American Psychological Association (APA)
Jin, Meiling& Xie, Yuansheng& Li, Qinggang& Chen, Xiangmei. 2014. Stem Cell-Based Cell Therapy for Glomerulonephritis. BioMed Research International،Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-447527
Modern Language Association (MLA)
Jin, Meiling…[et al.]. Stem Cell-Based Cell Therapy for Glomerulonephritis. BioMed Research International No. 2014 (2014), pp.1-15.
https://search.emarefa.net/detail/BIM-447527
American Medical Association (AMA)
Jin, Meiling& Xie, Yuansheng& Li, Qinggang& Chen, Xiangmei. Stem Cell-Based Cell Therapy for Glomerulonephritis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-447527
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447527