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Perioperative Nerve Blockade : Clues from the Bench
Joint Authors
Decosterd, I.
Siegenthaler, A.
Suter, M. R.
Ji, R. R.
Source
Anesthesiology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-12
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Peripheral and neuraxial nerve blockades are widely used in the perioperative period.
Their values to diminish acute postoperative pain are established but other important outcomes such as chronic postoperative pain, or newly, cancer recurrence, or infections could also be influenced.
The long-term effects of perioperative nerve blockade are still controversial.
We will review current knowledge of the effects of blocking peripheral electrical activity in different animal models of pain.
We will first go over the mechanisms of pain development and evaluate which types of fibers are activated after an injury.
In the light of experimental results, we will propose some hypotheses explaining the mitigated results obtained in clinical studies on chronic postoperative pain.
Finally, we will discuss three major disadvantages of the current blockade: the absence of blockade of myelinated fibers, the inappropriate duration of blockade, and the existence of activity-independent mechanisms.
American Psychological Association (APA)
Suter, M. R.& Siegenthaler, A.& Decosterd, I.& Ji, R. R.. 2011. Perioperative Nerve Blockade : Clues from the Bench. Anesthesiology Research and Practice،Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-447546
Modern Language Association (MLA)
Suter, M. R.…[et al.]. Perioperative Nerve Blockade : Clues from the Bench. Anesthesiology Research and Practice No. 2011 (2011), pp.1-12.
https://search.emarefa.net/detail/BIM-447546
American Medical Association (AMA)
Suter, M. R.& Siegenthaler, A.& Decosterd, I.& Ji, R. R.. Perioperative Nerve Blockade : Clues from the Bench. Anesthesiology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-447546
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447546