Emerging Insights into Antibiotic-Associated Diarrhea and Clostridium difficile Infection through the Lens of Microbial Ecology
Joint Authors
Walk, Seth T.
Young, Vincent B.
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-12-04
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Antibiotics are the main, and often only, clinical intervention for prophylactic and active treatment of bacterial infections in humans.
Perhaps it is not surprising that these drugs also shift the composition of commensal bacteria inside our bodies, especially those within the gut microbial community (microbiota).
How these dynamics ultimately affect the function of the gut microbiota, however, is not fully appreciated.
Likewise, how antibiotic induced changes facilitate the outgrowth and pathogenicity of certain bacterial strains remains largely enigmatic.
Here, we discuss the merits of a microbial ecology approach toward understanding a common side effect of antibiotic use, antibiotic-associated diarrhea (AAD), and the opportunistic bacterial infections that sometimes underlie it.
As an example, we discuss how this approach is being used to address complex disease dynamics during Clostridium difficile infection.
American Psychological Association (APA)
Walk, Seth T.& Young, Vincent B.. 2008. Emerging Insights into Antibiotic-Associated Diarrhea and Clostridium difficile Infection through the Lens of Microbial Ecology. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-447571
Modern Language Association (MLA)
Walk, Seth T.& Young, Vincent B.. Emerging Insights into Antibiotic-Associated Diarrhea and Clostridium difficile Infection through the Lens of Microbial Ecology. Interdisciplinary Perspectives on Infectious Diseases No. 2008 (2008), pp.1-7.
https://search.emarefa.net/detail/BIM-447571
American Medical Association (AMA)
Walk, Seth T.& Young, Vincent B.. Emerging Insights into Antibiotic-Associated Diarrhea and Clostridium difficile Infection through the Lens of Microbial Ecology. Interdisciplinary Perspectives on Infectious Diseases. 2008. Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-447571
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447571