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PPARδ Agonism for the Treatment of Obesity and Associated Disorders : Challenges and Opportunities
Joint Authors
Erbe, David V.
Tobin, James F.
Perreault, Mylène
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-10-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
The prevalence of obesity in the USA and worldwide has reached epidemic proportions during the last two decades.
Drugs currently available for the treatment of obesity provide no more than 5% placebo-adjusted weight loss and are associated with undesirable side effects.
Peroxisome proliferator-activated receptor (PPAR) modulators offer potential benefits for the treatment of obesity and its associated complications but their development has been complicated by biological, technical, and regulatory challenges.
Despite significant challenges, PPAR modulators are attractive targets for the treatment of obesity and could offer a viable alternative to the millions of patients who fail to lose weight following rigorous dieting and exercise protocols.
In addition, PPAR modulators have the potential-added benefit of ameliorating the associated comorbidities.
American Psychological Association (APA)
Perreault, Mylène& Erbe, David V.& Tobin, James F.. 2008. PPARδ Agonism for the Treatment of Obesity and Associated Disorders : Challenges and Opportunities. PPAR Research،Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-447603
Modern Language Association (MLA)
Perreault, Mylène…[et al.]. PPARδ Agonism for the Treatment of Obesity and Associated Disorders : Challenges and Opportunities. PPAR Research No. 2008 (2008), pp.1-9.
https://search.emarefa.net/detail/BIM-447603
American Medical Association (AMA)
Perreault, Mylène& Erbe, David V.& Tobin, James F.. PPARδ Agonism for the Treatment of Obesity and Associated Disorders : Challenges and Opportunities. PPAR Research. 2008. Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-447603
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447603