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Evaluation of the Mean Platelet Volume and Red Cell Distribution Width in FMF : Are They Related to Subclinical Inflammation or Not?
Joint Authors
Gokalp, İrem
Kesici-Metin, Fatma
Gul, Ozlem
Sayarlıoglu, Mehmet
Yildirim Cetin, Gozde
Source
International Journal of Chronic Diseases
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-12
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
In this paper we want to demonstrate whether higher than normal levels of RDW, and lower than normal levels of MPV can be used as indicators of subclinical inflammation and tools for treatment decision in FMF or not.
The participants in this study included 89 patients with FMF during attack-free periods and 30 healthy controls.
The RDW and platelet counts were significantly higher, while the MPV was significantly lower in the patients with FMF group than healthy control group (P<0.001; P=0.005; P<0.001, resp.).
In the attack-free FMF group, a negative correlation was found between the MPV and RDW values (P<0.001, r=-0.40).
The positive correlation was found between the RDW and ESR (r=0.23, P=0.028).
And the negative correlation was found between the MPV and CRP (r=-0.216, P=0.042).
Consequently, our results suggest that low MPV and high RDW levels may provide additional information about subclinical inflammation in FMF patients.
But other strong predisposing factors affecting subclinical inflammation in FMF should be considered.
Further studies with large numbers of patients are needed.
Treatment of FMF should include not only prevention of acute attacks but also decreasing of the subclinical inflammation.
American Psychological Association (APA)
Yildirim Cetin, Gozde& Gul, Ozlem& Kesici-Metin, Fatma& Gokalp, İrem& Sayarlıoglu, Mehmet. 2014. Evaluation of the Mean Platelet Volume and Red Cell Distribution Width in FMF : Are They Related to Subclinical Inflammation or Not?. International Journal of Chronic Diseases،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-447797
Modern Language Association (MLA)
Yildirim Cetin, Gozde…[et al.]. Evaluation of the Mean Platelet Volume and Red Cell Distribution Width in FMF : Are They Related to Subclinical Inflammation or Not?. International Journal of Chronic Diseases No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-447797
American Medical Association (AMA)
Yildirim Cetin, Gozde& Gul, Ozlem& Kesici-Metin, Fatma& Gokalp, İrem& Sayarlıoglu, Mehmet. Evaluation of the Mean Platelet Volume and Red Cell Distribution Width in FMF : Are They Related to Subclinical Inflammation or Not?. International Journal of Chronic Diseases. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-447797
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447797