The S-Layer Glycome—Adding to the Sugar Coat of Bacteria
Joint Authors
Schäffer, Christina
Messner, Paul
Zarschler, Kristof
Steiner, Kerstin
Ristl, Robin
Zayni, Sonja
Source
International Journal of Microbiology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-10
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Abstract EN
The amazing repertoire of glycoconjugates present on bacterial cell surfaces includes lipopolysaccharides, capsular polysaccharides, lipooligosaccharides, exopolysaccharides, and glycoproteins.
While the former are constituents of Gram-negative cells, we review here the cell surface S-layer glycoproteins of Gram-positive bacteria.
S-layer glycoproteins have the unique feature of self-assembling into 2D lattices providing a display matrix for glycans with periodicity at the nanometer scale.
Typically, bacterial S-layer glycans are O-glycosidically linked to serine, threonine, or tyrosine residues, and they rely on a much wider variety of constituents, glycosidic linkage types, and structures than their eukaryotic counterparts.
As the S-layer glycome of several bacteria is unravelling, a picture of how S-layer glycoproteins are biosynthesized is evolving.
X-ray crystallography experiments allowed first insights into the catalysis mechanism of selected enzymes.
In the future, it will be exciting to fully exploit the S-layer glycome for glycoengineering purposes and to link it to the bacterial interactome.
American Psychological Association (APA)
Ristl, Robin& Steiner, Kerstin& Zarschler, Kristof& Zayni, Sonja& Messner, Paul& Schäffer, Christina. 2010. The S-Layer Glycome—Adding to the Sugar Coat of Bacteria. International Journal of Microbiology،Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-447844
Modern Language Association (MLA)
Ristl, Robin…[et al.]. The S-Layer Glycome—Adding to the Sugar Coat of Bacteria. International Journal of Microbiology No. 2011 (2011), pp.1-16.
https://search.emarefa.net/detail/BIM-447844
American Medical Association (AMA)
Ristl, Robin& Steiner, Kerstin& Zarschler, Kristof& Zayni, Sonja& Messner, Paul& Schäffer, Christina. The S-Layer Glycome—Adding to the Sugar Coat of Bacteria. International Journal of Microbiology. 2010. Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-447844
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447844