A Role for Peroxisome Proliferator-Activated Receptors in the Immunopathology of Schistosomiasis?
Joint Authors
Li, Yuesheng S.
Anthony, Barrie J.
McManus, Donald P.
Allen, Jeremy T.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Peroxisome proliferator-activated receptors (PPARs) have been demonstrated to have a role in immune regulation.
In general, they are anti-inflammatory and promote Th2 type responses, and they are associated with the alternative activation of macrophages.
Interestingly, helminth infections, such as the schistosome blood flukes that cause schistosomiasis, are characterised by a Th2 response and the accumulation of alternative activated macrophages.
This would suggest that at some level, PPARs could have a role in the modulation of the immune response in schistosomiasis.
This paper discusses possible areas where PPARs could have a role in this disease.
American Psychological Association (APA)
Anthony, Barrie J.& Allen, Jeremy T.& Li, Yuesheng S.& McManus, Donald P.. 2011. A Role for Peroxisome Proliferator-Activated Receptors in the Immunopathology of Schistosomiasis?. PPAR Research،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-447860
Modern Language Association (MLA)
Anthony, Barrie J.…[et al.]. A Role for Peroxisome Proliferator-Activated Receptors in the Immunopathology of Schistosomiasis?. PPAR Research No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-447860
American Medical Association (AMA)
Anthony, Barrie J.& Allen, Jeremy T.& Li, Yuesheng S.& McManus, Donald P.. A Role for Peroxisome Proliferator-Activated Receptors in the Immunopathology of Schistosomiasis?. PPAR Research. 2011. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-447860
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447860