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Ligation Strategies for Targeting Liposomal Nanocarriers
Joint Authors
de Kroon, Anton I. P. M.
Marqués-Gallego, Patricia
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-14
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Liposomes have been exploited for pharmaceutical purposes, including diagnostic imaging and drug and gene delivery.
The versatility of liposomes as drug carriers has been demonstrated by a variety of clinically approved formulations.
Since liposomes were first reported, research of liposomal formulations has progressed to produce improved delivery systems.
One example of this progress is stealth liposomes, so called because they are equipped with a PEGylated coating of the liposome bilayer, leading to prolonged blood circulation and improved biodistribution of the liposomal carrier.
A growing research area focuses on the preparation of liposomes with the ability of targeting specific tissues.
Several strategies to prepare liposomes with active targeting ligands have been developed over the last decades.
Herein, several strategies for the functionalization of liposomes are concisely summarized, with emphasis on recently developed technologies for the covalent conjugation of targeting ligands to liposomes.
American Psychological Association (APA)
Marqués-Gallego, Patricia& de Kroon, Anton I. P. M.. 2014. Ligation Strategies for Targeting Liposomal Nanocarriers. BioMed Research International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-447993
Modern Language Association (MLA)
Marqués-Gallego, Patricia& de Kroon, Anton I. P. M.. Ligation Strategies for Targeting Liposomal Nanocarriers. BioMed Research International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-447993
American Medical Association (AMA)
Marqués-Gallego, Patricia& de Kroon, Anton I. P. M.. Ligation Strategies for Targeting Liposomal Nanocarriers. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-447993
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447993