Occult Cerebrovascular Disease and Late-Onset Epilepsy : Could Loss of Neurovascular Unit Integrity Be a Viable Model?
Joint Authors
Emsley, Hedley C. A.
Parkes, Laura M.
Allan, Stuart M.
Gibson, Lorna M.
Source
Cardiovascular Psychiatry and Neurology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-06
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Late-onset epilepsy (LOE) first occurs after 60 years of age and may be due to occult cerebrovascular disease (CVD) which confers an increased risk of stroke.
However, patients with late-onset epilepsy are not currently consistently investigated or treated for cerebrovascular risk factors.
We discuss how abnormalities of neurovascular unit function, namely, changes in regional cerebral blood flow and blood brain barrier disruption, may be caused by occult cerebrovascular disease but present clinically as late-onset epilepsy.
We describe novel magnetic resonance imaging methods to detect abnormal neurovascular unit function in subjects with LOE and controls.
We hypothesise that occult CVD may cause LOE as a result of neurovascular unit dysfunction.
American Psychological Association (APA)
Gibson, Lorna M.& Allan, Stuart M.& Parkes, Laura M.& Emsley, Hedley C. A.. 2011. Occult Cerebrovascular Disease and Late-Onset Epilepsy : Could Loss of Neurovascular Unit Integrity Be a Viable Model?. Cardiovascular Psychiatry and Neurology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-448071
Modern Language Association (MLA)
Gibson, Lorna M.…[et al.]. Occult Cerebrovascular Disease and Late-Onset Epilepsy : Could Loss of Neurovascular Unit Integrity Be a Viable Model?. Cardiovascular Psychiatry and Neurology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-448071
American Medical Association (AMA)
Gibson, Lorna M.& Allan, Stuart M.& Parkes, Laura M.& Emsley, Hedley C. A.. Occult Cerebrovascular Disease and Late-Onset Epilepsy : Could Loss of Neurovascular Unit Integrity Be a Viable Model?. Cardiovascular Psychiatry and Neurology. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-448071
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448071
