Parenteral Antibiotics Reduce Bifidobacteria Colonization and Diversity in Neonates
Joint Authors
Ross, R. Paul
Murphy, Brendan
Wall, Rebecca
Fitzgerald, Gerald
O'Sullivan, Lisa
Stanton, Catherine
Hussey, Séamus
Gruffman, Emma
Ryan, C. Anthony
Source
International Journal of Microbiology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Abstract EN
We investigated the impact of parenteral antibiotic treatment in the early neonatal period on the evolution of bifidobacteria in the newborn.
Nine babies treated with intravenous ampicillin/gentamicin in the first week of life and nine controls (no antibiotic treatment) were studied.
Denaturing gradient gel electrophoresis was used to investigate the composition of Bifidobacterium in stool samples taken at four and eight weeks.
Bifidobacteria were detected in all control infants at both four and eight weeks, while only six of nine antibiotic-treated infants had detectable bifidobacteria at four weeks and eight of nine at eight weeks.
Moreover, stool samples of controls showed greater diversity of Bifidobacterium spp.
compared with antibiotic-treated infants.
In conclusion, short-term parenteral antibiotic treatment of neonates causes a disturbance in the expected colonization pattern of bifidobacteria in the first months of life.
Further studies are required to probiotic determine if supplementation is necessary in this patient group.
American Psychological Association (APA)
Hussey, Séamus& Wall, Rebecca& Gruffman, Emma& O'Sullivan, Lisa& Ryan, C. Anthony& Murphy, Brendan…[et al.]. 2010. Parenteral Antibiotics Reduce Bifidobacteria Colonization and Diversity in Neonates. International Journal of Microbiology،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-448094
Modern Language Association (MLA)
Hussey, Séamus…[et al.]. Parenteral Antibiotics Reduce Bifidobacteria Colonization and Diversity in Neonates. International Journal of Microbiology No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-448094
American Medical Association (AMA)
Hussey, Séamus& Wall, Rebecca& Gruffman, Emma& O'Sullivan, Lisa& Ryan, C. Anthony& Murphy, Brendan…[et al.]. Parenteral Antibiotics Reduce Bifidobacteria Colonization and Diversity in Neonates. International Journal of Microbiology. 2010. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-448094
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448094