Type 2 Innate Lymphoid Cells : Friends or Foes—Role in Airway Allergic Inflammation and Asthma
Joint Authors
Varasteh, Abdol-ReZa
Sankian, Mojtaba
Pishdadian, Abbas
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-11
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Innate-like lymphocytes (ILLs) and innate lymphoid cells (ILCs) are two newly characterized families of lymphocytes with limited and no rearranged antigen receptors, respectively.
These soldiers provide a first line of defense against foreign insults by triggering a prompt innate immune response and bridging the gap of innate and adaptive immunity.
Type 2 innate lymphoid cells (ILCs2) are newly identified members of the ILC family that play a key role in type 2 immune responses by prompt production of type 2 cytokines (especially IL-5 and IL-13) in response to antigen-induced IL-25/33 and by recruiting type 2 “immune franchise.” Regarding the two different roles of type 2 cytokines, helminth expulsion and type 2-related diseases, here we review the latest advances in ILC2 biology and examine the pivotal role of resident ILCs2 in allergen-specific airway inflammation and asthma.
American Psychological Association (APA)
Pishdadian, Abbas& Varasteh, Abdol-ReZa& Sankian, Mojtaba. 2012. Type 2 Innate Lymphoid Cells : Friends or Foes—Role in Airway Allergic Inflammation and Asthma. Journal of Allergy،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-448136
Modern Language Association (MLA)
Pishdadian, Abbas…[et al.]. Type 2 Innate Lymphoid Cells : Friends or Foes—Role in Airway Allergic Inflammation and Asthma. Journal of Allergy No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-448136
American Medical Association (AMA)
Pishdadian, Abbas& Varasteh, Abdol-ReZa& Sankian, Mojtaba. Type 2 Innate Lymphoid Cells : Friends or Foes—Role in Airway Allergic Inflammation and Asthma. Journal of Allergy. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-448136
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448136