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Biliary Atresia : 50 Years after the First Kasai
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-06
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Biliary atresia is a rare neonatal disease of unknown etiology, where obstruction of the biliary tree causes severe cholestasis, leading to biliary cirrhosis and death in the first years of life, if the condition is left untreated.
Biliary atresia is the most frequent surgical cause of cholestatic jaundice in neonates and should be evoked whenever this clinical sign is associated with pale stools and hepatomegaly.
The treatment of biliary atresia is surgical and currently recommended as a sequence of, eventually, two interventions.
During the first months of life a hepatoportoenterostomy (a “Kasai,” modifications of which are discussed in this paper) should be performed, in order to restore the biliary flow to the intestine and lessen further damage to the liver.
If this fails and/or the disease progresses towards biliary cirrhosis and life-threatening complications, then liver transplantation is indicated, for which biliary atresia represents the most frequent pediatric indication.
Of importance, the earlier the Kasai is performed, the later a liver transplantation is usually needed.
This warrants a great degree of awareness of biliary atresia, and the implementation of systematic screening for this life-threatening pathology.
American Psychological Association (APA)
Wildhaber, Barbara E.. 2012. Biliary Atresia : 50 Years after the First Kasai. ISRN Surgery،Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-448227
Modern Language Association (MLA)
Wildhaber, Barbara E.. Biliary Atresia : 50 Years after the First Kasai. ISRN Surgery No. 2012 (2012), pp.1-15.
https://search.emarefa.net/detail/BIM-448227
American Medical Association (AMA)
Wildhaber, Barbara E.. Biliary Atresia : 50 Years after the First Kasai. ISRN Surgery. 2012. Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-448227
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448227