Acute Kidney Injury after Major Abdominal Surgery : A Retrospective Cohort Analysis
Joint Authors
Teixeira, Catarina
Bicha Castelo, Henrique
Pereira, Marta
Rosa, Rosário
Mendes, Inês
Lopes, José António
Peixoto, Lígia
Dias, Sofia
Melo, Maria João
Rodrigues, Natacha
Source
Critical Care Research and Practice
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
We analyzed the incidence, risk factors, and prognosis of acute kidney injury (AKI) in a cohort of patients undergoing major abdominal surgery.
Methods.
A total of 450 patients were retrospectively studied.
AKI was defined by an increase in serum creatinine (SCr) ≥ 0.3 mg/dl or by an increase in SCr ≥ 50% and/or by a decrease in urine output to 0.5 ml/kg/hour for 6 hours, in the first 48 hours after surgery.
Logistic regression method was used to determine predictors of AKI and in-hospital mortality.
A two-tailed P value <0.05 was considered significant.
Results.
One hundred one patients (22.4%) had postoperative AKI.
Age (adjusted odds ratio (OR) 1.02, 95% confidence interval (CI) 1.01–1.05), nonrenal Revised Cardiac Risk Index score (adjusted OR 1.9, 95% CI 1.3–3.1, P=0.003), intraoperative erythrocytes transfusions (adjusted OR 2.2, 95% CI 1.4–3.5, P <.0001), and nonrenal Simplified Acute Physiology Score II (adjusted OR 1.03, 95% CI 1.01–1.06, P=0.0191) were associated with postoperative AKI.
AKI was associated with increased in-hospital mortality (20.8% versus 2.3%, P <.0001; unadjusted OR 11.2, 95% CI 4.8–26.2, P <.0001; adjusted OR 3.7, 95% CI 1.2–11.7, P=0.024).
Conclusion.
AKI was common in patients undergoing major abdominal surgery and was associated with in-hospital mortality.
American Psychological Association (APA)
Teixeira, Catarina& Rosa, Rosário& Rodrigues, Natacha& Mendes, Inês& Peixoto, Lígia& Dias, Sofia…[et al.]. 2014. Acute Kidney Injury after Major Abdominal Surgery : A Retrospective Cohort Analysis. Critical Care Research and Practice،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-448237
Modern Language Association (MLA)
Teixeira, Catarina…[et al.]. Acute Kidney Injury after Major Abdominal Surgery : A Retrospective Cohort Analysis. Critical Care Research and Practice No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-448237
American Medical Association (AMA)
Teixeira, Catarina& Rosa, Rosário& Rodrigues, Natacha& Mendes, Inês& Peixoto, Lígia& Dias, Sofia…[et al.]. Acute Kidney Injury after Major Abdominal Surgery : A Retrospective Cohort Analysis. Critical Care Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-448237
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448237