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Serum Insulin-Like Growth Factor-1 and Nitric Oxide Levels in Parkinson's Disease
Joint Authors
Inanc Tolun, Fatma
Toru, Ismail
Tuncel, Deniz
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-03-12
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The aim of this study was to investigate the role of circulating growth hormone (GH), insulin growth factor-1 (IGF-1), IGF binding protein-3 (IGFBP-3), and nitric oxide (NO) concentrations in the patients suffering from Parkinson's disease (PD).
The study groups were consisted of 25 patients with PD and 25 matched healthy subjects as a control.
The NO level of patients in PD group (2.3±0.4 μmol/L) was significantly lower than that in the control group (2.8±0.6 μmol/L) (P:.011).
Although there were no statistically significant differences in the GH, IGF-1, and IGF BP-3 levels among the two groups, in this preliminary study, we found low NO and mildly elevated IGF-1 levels in the patients with PD.
The results may be associated with adaptation or protective mechanisms in the neurodegenerative disease processes such as seen in the PD.
Further studies should be carried out to confirm our results.
American Psychological Association (APA)
Tuncel, Deniz& Inanc Tolun, Fatma& Toru, Ismail. 2009. Serum Insulin-Like Growth Factor-1 and Nitric Oxide Levels in Parkinson's Disease. Mediators of Inflammation،Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-448262
Modern Language Association (MLA)
Tuncel, Deniz…[et al.]. Serum Insulin-Like Growth Factor-1 and Nitric Oxide Levels in Parkinson's Disease. Mediators of Inflammation No. 2009 (2009), pp.1-4.
https://search.emarefa.net/detail/BIM-448262
American Medical Association (AMA)
Tuncel, Deniz& Inanc Tolun, Fatma& Toru, Ismail. Serum Insulin-Like Growth Factor-1 and Nitric Oxide Levels in Parkinson's Disease. Mediators of Inflammation. 2009. Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-448262
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448262