Bone-Marrow-Derived Mesenchymal Stem Cells for Organ Repair
Joint Authors
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
Mesenchymal stem cells (MSCs) are prototypical adult stem cells with the capacity for self-renewal and differentiation with a broad tissue distribution.
MSCs not only differentiate into types of cells of mesodermal lineage but also into endodermal and ectodermal lineages such as bone, fat, cartilage and cardiomyocytes, endothelial cells, lung epithelial cells, hepatocytes, neurons, and pancreatic islets.
MSCs have been identified as an adherent, fibroblast-like population and can be isolated from different adult tissues, including bone marrow (BM), umbilical cord, skeletal muscle, and adipose tissue.
MSCs secrete factors, including IL-6, M-CSF, IL-10, HGF, and PGE2, that promote tissue repair, stimulate proliferation and differentiation of endogenous tissue progenitors, and decrease inflammatory and immune reactions.
In this paper, we focus on the role of BM-derived MSCs in organ repair.
American Psychological Association (APA)
Li, Ming& Ikehara, Susumu. 2013. Bone-Marrow-Derived Mesenchymal Stem Cells for Organ Repair. Stem Cells International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-448282
Modern Language Association (MLA)
Li, Ming& Ikehara, Susumu. Bone-Marrow-Derived Mesenchymal Stem Cells for Organ Repair. Stem Cells International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-448282
American Medical Association (AMA)
Li, Ming& Ikehara, Susumu. Bone-Marrow-Derived Mesenchymal Stem Cells for Organ Repair. Stem Cells International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-448282
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448282