A Simplified 3D Model of Whole Heart Electrical Activity and 12-Lead ECG Generation
Joint Authors
Magjarević, Ratko
Lovell, Nigel H.
Sovilj, Siniša
Dokos, Socrates
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-22
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
We present a computationally efficient three-dimensional bidomain model of torso-embedded whole heart electrical activity, with spontaneous initiation of activation in the sinoatrial node, incorporating a specialized conduction system with heterogeneous action potential morphologies throughout the heart.
The simplified geometry incorporates the whole heart as a volume source, with heart cavities, lungs, and torso as passive volume conductors.
We placed four surface electrodes at the limbs of the torso: VR, VL, VF and VGND and six electrodes on the chest to simulate the Einthoven, Goldberger-augmented and precordial leads of a standard 12-lead system.
By placing additional seven electrodes at the appropriate torso positions, we were also able to calculate the vectorcardiogram of the Frank lead system.
Themodel was able to simulate realistic electrocardiogram (ECG) morphologies for the 12 standard leads, orthogonal X, Y, and Z leads, as well as the vectorcardiogram under normal and pathological heart states.
Thus, simplified and easy replicable 3D cardiac bidomain model offers a compromise between computational load and model complexity and can be used as an investigative tool to adjust cell, tissue, and whole heart properties, such as setting ischemic lesions or regions of myocardial infarction, to readily investigate their effects on whole ECG morphology.
American Psychological Association (APA)
Sovilj, Siniša& Magjarević, Ratko& Lovell, Nigel H.& Dokos, Socrates. 2013. A Simplified 3D Model of Whole Heart Electrical Activity and 12-Lead ECG Generation. Computational and Mathematical Methods in Medicine،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-448345
Modern Language Association (MLA)
Sovilj, Siniša…[et al.]. A Simplified 3D Model of Whole Heart Electrical Activity and 12-Lead ECG Generation. Computational and Mathematical Methods in Medicine No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-448345
American Medical Association (AMA)
Sovilj, Siniša& Magjarević, Ratko& Lovell, Nigel H.& Dokos, Socrates. A Simplified 3D Model of Whole Heart Electrical Activity and 12-Lead ECG Generation. Computational and Mathematical Methods in Medicine. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-448345
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448345