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Small-for-Gestational-Age Births in Pregnant Women with HIV, due to Severity of HIV Disease, Not Antiretroviral Therapy
Joint Authors
Aaron, Erika
Culhane, Jennifer F.
Alleyne, Gregg
Bamford, Laura P.
Mathew, Leny
Bonacquisti, Alexa
Source
Infectious Diseases in Obstetrics and Gynecology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-20
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objectives.
To determine rate and factors associated with small-for-gestational-age (SGA) births to women with HIV.
Methods.
Prospective data were collected from 183 pregnant women with HIV in an urban HIV prenatal clinic, 2000–2011.
An SGA birth was defined as less than the 10th or 3rd percentile of birth weight distribution based upon cut points developed using national vital record data.
Bivariate analysis utilized chi-squared and t-tests, and multiple logistic regression analyses were used.
Results.
The prevalence of SGA was 31.2% at the 10th and 12.6% at the 3rd percentile.
SGA at the 10th (OR 2.77; 95% CI, 1.28–5.97) and 3rd (OR 3.64; 95% CI, 1.12–11.76) percentiles was associated with cigarette smoking.
Women with CD4 count >200 cells/mm3 at the first prenatal visit were less likely to have an SGA birth at the 3rd percentile (OR 0.29; 95% CI, 0.10–0.86).
Women taking NNRTI were less likely to have an SGA infant at the 10th (OR 0.28; 95% CI, 0.10–0.75) and 3rd (OR 0.16; 95% CI, 0.03–0.91) percentiles compared to those women on PIs.
Conclusions.
In this cohort with high rates of SGA, severity of HIV disease, not ART, was associated with SGA births after adjusting for sociodemographic, medication, and disease severity.
American Psychological Association (APA)
Aaron, Erika& Bonacquisti, Alexa& Mathew, Leny& Alleyne, Gregg& Bamford, Laura P.& Culhane, Jennifer F.. 2012. Small-for-Gestational-Age Births in Pregnant Women with HIV, due to Severity of HIV Disease, Not Antiretroviral Therapy. Infectious Diseases in Obstetrics and Gynecology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-448434
Modern Language Association (MLA)
Aaron, Erika…[et al.]. Small-for-Gestational-Age Births in Pregnant Women with HIV, due to Severity of HIV Disease, Not Antiretroviral Therapy. Infectious Diseases in Obstetrics and Gynecology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-448434
American Medical Association (AMA)
Aaron, Erika& Bonacquisti, Alexa& Mathew, Leny& Alleyne, Gregg& Bamford, Laura P.& Culhane, Jennifer F.. Small-for-Gestational-Age Births in Pregnant Women with HIV, due to Severity of HIV Disease, Not Antiretroviral Therapy. Infectious Diseases in Obstetrics and Gynecology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-448434
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448434