![](/images/graphics-bg.png)
A Cytohistologic Correlation of Mucoepidermoid Carcinoma : Emphasizing the Rare Oncocytic Variant
Joint Authors
Wade, Timothy V.
Baloch, Zubair W.
Montone, Kathleen T.
Livolsi, Virginia A.
Source
Pathology Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
It is well-known that the morphological variability of mucoepidermoid carcinoma (MEC) of the salivary glands may lead to interpretative difficulties on fine-needle aspiration (FNA) diagnosis.
In this study we identify morphologic features that may be useful in the FNA diagnosis of MEC.
The cohort included 23 cases of MEC; cytology and histology slides were reviewed and assessed for % cystic component, extracellular mucin, mucous and intermediate cells, oncocytes, cells with foamy/clear cytoplasm, keratinized cells and lymphocytes.
On FNA 12/23 (52%) cases were diagnosed as consistent with or suggestive of MEC; 6/23 (26%) as salivary gland neoplasm and 5/23 (22%) as no tumor seen.
The cystic component was ≥50% in 18/23 (78%) and <50% in 5 cases.
The features prevalent in FNA and histology were: mucous cells (96% and 91%), extracellular mucin (91% both), intermediate cells (100 and 83%), lymphocytes (96 and 78%) and cells with foamy/clear cytoplasm (74% both).
Oncocytes were seen in 43 and 22% and keratinized cells in 48 and 13% cases.
Cases with oncocytes and lymphocytes were interpreted as favor Warthin's tumor on FNA.
Presence of mucous cells, cells with foamy/clear cytoplasm, intermediate cells and lymphocytes in a mucinous background are diagnostic indicators of MEC; presence of oncocytes should not refrain from diagnosing MEC in FNA specimens.
American Psychological Association (APA)
Wade, Timothy V.& Livolsi, Virginia A.& Montone, Kathleen T.& Baloch, Zubair W.. 2011. A Cytohistologic Correlation of Mucoepidermoid Carcinoma : Emphasizing the Rare Oncocytic Variant. Pathology Research International،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-448508
Modern Language Association (MLA)
Wade, Timothy V.…[et al.]. A Cytohistologic Correlation of Mucoepidermoid Carcinoma : Emphasizing the Rare Oncocytic Variant. Pathology Research International No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-448508
American Medical Association (AMA)
Wade, Timothy V.& Livolsi, Virginia A.& Montone, Kathleen T.& Baloch, Zubair W.. A Cytohistologic Correlation of Mucoepidermoid Carcinoma : Emphasizing the Rare Oncocytic Variant. Pathology Research International. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-448508
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448508