Effects of Exercise on Oxidative Stress in Rats Induced by Ozone
Joint Authors
Kross, Robert David
Lara-Padilla, Eleazar
Villanueva, Cleva
Bobadilla-Lugo, Rosa Amalia
Martinez-Campos, Catalina
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-24
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Oxidative stress (OS) induced by acute exercise is reduced by chronic exercise.
Ozone (O3) exposure produces OS.
The aim of this study was to determine if aerobic exercise (AE) reduced OS produced by O3.
A pilot experiment was performed with male Wistar rats submitted to AE (trained to swim 90 min/day).
Adaptation to exercise was demonstrated three weeks after training by means of changes in reduced nitrates (NOx) in plasma.
Therefore, two-week training was chosen for the following experiments.
Six of twelve trained rats were exposed to O3 (0.5 ppm, 4 h/day, one hour before exercise).
Two groups of sedentary animals (n=6 each) were used as controls, one of which was exposed to O3.
At the end of the experiments NOx, 8-isoprostane (8-IP), malondialdehyde (MDA), superoxide dismutase (SOD) activity, and carbonyls (CBs) were measured in plasma.
CBs did not change in any group.
O3-induced OS was manifested by reduced NOx and SOD activity, as well as increased 8-IP and MDA.
Exercise significantly blocked O3 effects although SOD was also decreased by exercise (a greater drop occurring in the O3 group).
It is concluded that AE protects against OS produced by O3 and the effect is independent of SOD.
American Psychological Association (APA)
Martinez-Campos, Catalina& Lara-Padilla, Eleazar& Bobadilla-Lugo, Rosa Amalia& Kross, Robert David& Villanueva, Cleva. 2012. Effects of Exercise on Oxidative Stress in Rats Induced by Ozone. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-448523
Modern Language Association (MLA)
Martinez-Campos, Catalina…[et al.]. Effects of Exercise on Oxidative Stress in Rats Induced by Ozone. The Scientific World Journal No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-448523
American Medical Association (AMA)
Martinez-Campos, Catalina& Lara-Padilla, Eleazar& Bobadilla-Lugo, Rosa Amalia& Kross, Robert David& Villanueva, Cleva. Effects of Exercise on Oxidative Stress in Rats Induced by Ozone. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-448523
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448523