Ancillary Studies in Determining Human Papillomavirus Status of Squamous Cell Carcinoma of the Oropharynx : A Review
Joint Authors
Montebelli, Francesco
Cimbaluk, David
Gattuso, Paolo
Petruzzelli, G. J.
Cantley, Richard L.
Gabrielli, Eleonora
Source
Pathology Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Squamous cell carcinoma (SCC) of the oral cavity and pharynx represents the sixth most common form of malignancy worldwide.
A significant proportion of these cases are related to human papillomavirus (HPV) infection.
In general, HPV-associated SCC is more commonly nonkeratinizing and poorly differentiated, whereas non-HPV-associated SCC is typically keratinizing and moderately differentiated.
Nevertheless, significant overlap in morphology is seen between these two forms of SCC.
The purpose of this paper is to highlight the utility of ancillary studies in the establishment of HPV status of oropharyngeal SCC, including p16 immunohistochemistry, high-risk HPV in situ hybridization, polymerase chain reaction, and newer HPV detection modalities.
American Psychological Association (APA)
Cantley, Richard L.& Gabrielli, Eleonora& Montebelli, Francesco& Cimbaluk, David& Gattuso, Paolo& Petruzzelli, G. J.. 2011. Ancillary Studies in Determining Human Papillomavirus Status of Squamous Cell Carcinoma of the Oropharynx : A Review. Pathology Research International،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-448764
Modern Language Association (MLA)
Cantley, Richard L.…[et al.]. Ancillary Studies in Determining Human Papillomavirus Status of Squamous Cell Carcinoma of the Oropharynx : A Review. Pathology Research International No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-448764
American Medical Association (AMA)
Cantley, Richard L.& Gabrielli, Eleonora& Montebelli, Francesco& Cimbaluk, David& Gattuso, Paolo& Petruzzelli, G. J.. Ancillary Studies in Determining Human Papillomavirus Status of Squamous Cell Carcinoma of the Oropharynx : A Review. Pathology Research International. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-448764
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448764