Drug Nanoparticle Formulation Using Ascorbic Acid Derivatives
Joint Authors
Limwikrant, Waree
Yamamoto, Keiji
Moribe, Kunikazu
Higashi, Kenjirou
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-26
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Drug nanoparticle formulation using ascorbic acid derivatives and its therapeutic uses have recently been introduced.
Hydrophilic ascorbic acid derivatives such as ascorbyl glycoside have been used not only as antioxidants but also as food and pharmaceutical excipients.
In addition to drug solubilization, drug nanoparticle formation was observed using ascorbyl glycoside.
Hydrophobic ascorbic acid derivatives such as ascorbyl mono- and di-n-alkyl fatty acid derivatives are used either as drugs or carrier components.
Ascorbyl n-alkyl fatty acid derivatives have been formulated as antioxidants or anticancer drugs for nanoparticle formulations such as micelles, microemulsions, and liposomes.
ASC-P vesicles called aspasomes are submicron-sized particles that can encapsulate hydrophilic drugs.
Several transdermal and injectable formulations of ascorbyl n-alkyl fatty acid derivatives were used, including ascorbyl palmitate.
American Psychological Association (APA)
Moribe, Kunikazu& Limwikrant, Waree& Higashi, Kenjirou& Yamamoto, Keiji. 2011. Drug Nanoparticle Formulation Using Ascorbic Acid Derivatives. Journal of Drug Delivery،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-448809
Modern Language Association (MLA)
Moribe, Kunikazu…[et al.]. Drug Nanoparticle Formulation Using Ascorbic Acid Derivatives. Journal of Drug Delivery No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-448809
American Medical Association (AMA)
Moribe, Kunikazu& Limwikrant, Waree& Higashi, Kenjirou& Yamamoto, Keiji. Drug Nanoparticle Formulation Using Ascorbic Acid Derivatives. Journal of Drug Delivery. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-448809
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448809