Trends and Advances in Separation and Detection of SSRIs and SNRIs in Biological Matrices
Joint Authors
Source
Chromatography Research International
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-31
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Nowadays antidepressant drugs like selective serotonin reuptake inhibitors (SSRIs) and selective norepinephrine reuptake inhibitors (SNRIs) represent the first choice in the treatment of moderate to severe depressive illness, various phobias, and personality disorders.
In spite of the therapeutic aspects, they often produce very severe and toxic effects in deliberate and accidental cases of poisoning.
These are also considered as date-rape drugs used for drugged victims for raping or robbing.
Therefore, in recent years, their analyses in different biological matrices for clinical and toxicological analysis purposes has been a target worthy of interest.
Thus, the review focuses on recent advancements of various separation techniques like chromatography and electrophoresis that are concernd with the determination of selective serotonin reuptake inhibitor and selective norepinephrine reuptake inhibitor drugs and their metabolites in various biological matrices.
In addition to this, a critical discussion on analytical approaches has also been incorporated, suggesting their applicability and limitations for further implementations.
Thus, this paper will definitely help in the selection and development of proper analytical methodologies to achieve satisfactory results, better scientific understanding, and test interpretation.
American Psychological Association (APA)
Das, Ruchita& Agrawal, Y. K.. 2013. Trends and Advances in Separation and Detection of SSRIs and SNRIs in Biological Matrices. Chromatography Research International،Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-448863
Modern Language Association (MLA)
Das, Ruchita& Agrawal, Y. K.. Trends and Advances in Separation and Detection of SSRIs and SNRIs in Biological Matrices. Chromatography Research International No. 2013 (2013), pp.1-15.
https://search.emarefa.net/detail/BIM-448863
American Medical Association (AMA)
Das, Ruchita& Agrawal, Y. K.. Trends and Advances in Separation and Detection of SSRIs and SNRIs in Biological Matrices. Chromatography Research International. 2013. Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-448863
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448863