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Nuclear Receptors in Nonalcoholic Fatty Liver Disease
Joint Authors
Uribe, Misael
Méndez-Sánchez, Nahum
López-Velázquez, Jorge A.
Carrillo-Córdova, Luis D.
Chávez-Tapia, Norberto C.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-08
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Nuclear receptors comprise a superfamily of ligand-activated transcription factors that are involved in important aspects of hepatic physiology and pathophysiology.
There are about 48 nuclear receptors in the human.
These nuclear receptors are regulators of many hepatic processes including hepatic lipid and glucose metabolism, bile acid homeostasis, drug detoxification, inflammation, regeneration, fibrosis, and tumor formation.
Some of these receptors are sensitive to the levels of molecules that control lipid metabolism including fatty acids, oxysterols, and lipophilic molecules.
These receptors direct such molecules to the transcriptional networks and may play roles in the pathogenesis and treatment of nonalcoholic fatty liver disease.
Understanding the mechanisms underlying the involvement of nuclear receptors in the pathogenesis of nonalcoholic fatty liver disease may offer targets for the development of new treatments for this liver disease.
American Psychological Association (APA)
López-Velázquez, Jorge A.& Carrillo-Córdova, Luis D.& Chávez-Tapia, Norberto C.& Uribe, Misael& Méndez-Sánchez, Nahum. 2011. Nuclear Receptors in Nonalcoholic Fatty Liver Disease. Journal of Lipids،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-448903
Modern Language Association (MLA)
López-Velázquez, Jorge A.…[et al.]. Nuclear Receptors in Nonalcoholic Fatty Liver Disease. Journal of Lipids No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-448903
American Medical Association (AMA)
López-Velázquez, Jorge A.& Carrillo-Córdova, Luis D.& Chávez-Tapia, Norberto C.& Uribe, Misael& Méndez-Sánchez, Nahum. Nuclear Receptors in Nonalcoholic Fatty Liver Disease. Journal of Lipids. 2011. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-448903
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448903