Avidity of Antibodies against HSV-2 and Risk to Neonatal Transmission among Mexican Pregnant Women
Joint Authors
Vergara-Ortega, Dayana Nicté
Herrera-Ortiz, Antonia
Olamendi-Portugal, Ma. Leonidez
Conde-Glez, Carlos Jesús
García-Cisneros, Santa
Sánchez-Alemán, Miguel Angel
Source
Infectious Diseases in Obstetrics and Gynecology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-06
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To determine HSV-2 seroprevalence, risk factors, and antibody avidity among a sample of Mexican pregnant women.
Material and Methods.
The avidity test was standardized with different urea concentrations and incubation times; the cut-off point was calculated to determine the low avidity (early infection).
IgG antibodies against HSV-2 were detected from pregnant and postpartum women from Morelos, Mexico, and the avidity test was performed to positive samples.
Multivariate regression logistic analysis was employed to evaluate demographic and sexual behavior characteristics associated with HSV-2 infection.
Results.
HSV-2 seroprevalence among Mexican women analyzed was 14.5% (333/2300), demographic factors (location of General Hospital, age, education level, and civil status), and risky sexual behaviors (STI self-report and number of sexual partners during last year) were associated with HSV-2 infection.
Seventeen women were detected with low avidity antibodies (early infection) with a cut-off point of 66.1%.
Conclusions.
HSV-2 infection was common among this group of women from Mexico; the avidity test detected women with recent infections, and these women were more likely to transmit HSV-2 to their neonates.
Neonatal herpes has no epidemiological surveillance, the disease could be overlooked, and so more studies are needed to estimate the magnitude of neonatal infection.
American Psychological Association (APA)
Herrera-Ortiz, Antonia& Conde-Glez, Carlos Jesús& Vergara-Ortega, Dayana Nicté& García-Cisneros, Santa& Olamendi-Portugal, Ma. Leonidez& Sánchez-Alemán, Miguel Angel. 2013. Avidity of Antibodies against HSV-2 and Risk to Neonatal Transmission among Mexican Pregnant Women. Infectious Diseases in Obstetrics and Gynecology،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-448913
Modern Language Association (MLA)
Herrera-Ortiz, Antonia…[et al.]. Avidity of Antibodies against HSV-2 and Risk to Neonatal Transmission among Mexican Pregnant Women. Infectious Diseases in Obstetrics and Gynecology No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-448913
American Medical Association (AMA)
Herrera-Ortiz, Antonia& Conde-Glez, Carlos Jesús& Vergara-Ortega, Dayana Nicté& García-Cisneros, Santa& Olamendi-Portugal, Ma. Leonidez& Sánchez-Alemán, Miguel Angel. Avidity of Antibodies against HSV-2 and Risk to Neonatal Transmission among Mexican Pregnant Women. Infectious Diseases in Obstetrics and Gynecology. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-448913
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448913