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Endometriosis and Ovarian Cancer : A Systematic Review
Joint Authors
Crawford, Robin
Tsivos, Dimitris
Sayasneh, Ahmad
Source
ISRN Obstetrics and Gynecology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction.
Endometriosis is one of the most common benign disorders which affects 10–15% of all women in reproductive age.
The association between endometriosis and ovarian cancer has been frequently described in the medical literature.
Purpose.
To evaluate the literature for evidence of a correlation between endometriosis and ovarian cancer.
Method.
the English language literature (online MEDLINE and EMBASE database) was searched using the keywords endometriosis combined with cancer, tumour, tumor, carcinoma, or adenocarcinoma.
All abstracts between January 1985 and August 2010 were reviewed.
Full relevant articles were critically assessed.
Reference lists of included studies were checked.
Results.
Seven out of the eight studies, included in our review, have shown an increased risk of ovarian cancer.
However, the effect size is modest (OR, RR, and SIR) ranging between 1.32 and 1.9 (95% CI).
A causative relationship between the two incidences cannot be confirmed.
There is increasing evidence on the role of genetic mutations in ovarian clear-cell and endometrioid carcinoma developing from endometriosis.
Conclusion.
More evidence is needed before suggesting any change in the current management of endometriosis.
American Psychological Association (APA)
Sayasneh, Ahmad& Tsivos, Dimitris& Crawford, Robin. 2011. Endometriosis and Ovarian Cancer : A Systematic Review. ISRN Obstetrics and Gynecology،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-448929
Modern Language Association (MLA)
Sayasneh, Ahmad…[et al.]. Endometriosis and Ovarian Cancer : A Systematic Review. ISRN Obstetrics and Gynecology No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-448929
American Medical Association (AMA)
Sayasneh, Ahmad& Tsivos, Dimitris& Crawford, Robin. Endometriosis and Ovarian Cancer : A Systematic Review. ISRN Obstetrics and Gynecology. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-448929
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448929