Clinicopathological and Prognostic Characteristics of Hepatoid Adenocarcinoma of the Stomach
Joint Authors
Wang, Rui
Zhuang, Wen
Yang, Jin-Lin
Tang, Chengwei
Wang, Mo-Jin
Zhang, Wenyan
Source
Gastroenterology Research and Practice
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-11
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The present study was undertaken to clarify the association of the clinicopathological features of hepatoid adenocarcinoma (HAC) in the stomach, a special kind of carcinoma that histologically resembled hepatocellular carcinoma (HCC) and is characterized by large amounts of α-fetoprotein (AFP) in serum, with the clinical prognosis.
We collected the data of the clinicopathological features and the follow-up information from a total of 31 HACs from January 2005 to December 2012 in our hospital.
High lymphatic (54.8%) and distant (25.8%) metastasis rates before surgery, large proportion of advanced HACs (71.0%) at admission, short median overall survival time (6 months), and low three-year survival rate (22.6%) suggested that HAC in the stomach was an aggressive disease, resulting in a poor prognosis.
And pTNM stages, immunohistochemical staining of AFP, CEA, CK7, and CK20 had statistically relation with the survival as the independent risk factors, P<0.05.
Therefore, early and clear differentiation of HAC from cancerous or noncancerous conditions with AFP elevation and assessment of high risk patients by histopathology may improve the clinical prognosis.
American Psychological Association (APA)
Yang, Jin-Lin& Wang, Rui& Zhang, Wenyan& Zhuang, Wen& Wang, Mo-Jin& Tang, Chengwei. 2014. Clinicopathological and Prognostic Characteristics of Hepatoid Adenocarcinoma of the Stomach. Gastroenterology Research and Practice،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-448960
Modern Language Association (MLA)
Yang, Jin-Lin…[et al.]. Clinicopathological and Prognostic Characteristics of Hepatoid Adenocarcinoma of the Stomach. Gastroenterology Research and Practice No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-448960
American Medical Association (AMA)
Yang, Jin-Lin& Wang, Rui& Zhang, Wenyan& Zhuang, Wen& Wang, Mo-Jin& Tang, Chengwei. Clinicopathological and Prognostic Characteristics of Hepatoid Adenocarcinoma of the Stomach. Gastroenterology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-448960
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448960