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Comparison of Intrathecal Use of Isobaric and Hyperbaric Bupivacaine during Lower Abdomen Surgery
Joint Authors
Suwondo, Bambang S.
Uyun, Yusmein
Helmi, Mochamat
Widodo, Untung
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-05
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objective.
The ideal local anesthetic solution for intrathecal use has rapid onset and reliable duration, with less incidence of adverse events.
This study was aiming to compare the onset of anesthesia and duration of action of isobaric and hyperbaric bupivacaine for subarachnoid block (SAB).
Methods.
Sixty patients who underwent lower abdominal, hips, and lower extremity surgeries were randomized into two groups.
Group I received 20 mg of 0.5% isobaric bupivacaine, while Group H received 20 mg of 0.5% hyperbaric bupivacaine.
Injection was made intrattecally in midline position at L3-4 interspace in sitting position.
Results.
The onset of analgesia and motor blocks with isobaric was faster when compared to hyperbaric bupivacaine (4.8 ± 2.2 versus 7.5 ± 2.2 minutes and 4.1 ± 2.1 versus 6.4 ± 2.4 minutes, resp., P<0.001).
The duration of sensory and motor blocks was longer in isobaric when compared to hyperbaric bupivacaine (276 ± 30 versus 163 ± 22 minutes and 266 ± 32 versus 163 ± 24 minutes, P<0.001).
In both groups, hemodynamic changes were not clinically relevant, and the adverse effects were comparable.
Conclusion.
Isobaric produced more rapid onset and longer duration when compared to hyperbaric bupivacaine.
American Psychological Association (APA)
Helmi, Mochamat& Uyun, Yusmein& Suwondo, Bambang S.& Widodo, Untung. 2014. Comparison of Intrathecal Use of Isobaric and Hyperbaric Bupivacaine during Lower Abdomen Surgery. Journal of Anesthesiology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-449022
Modern Language Association (MLA)
Helmi, Mochamat…[et al.]. Comparison of Intrathecal Use of Isobaric and Hyperbaric Bupivacaine during Lower Abdomen Surgery. Journal of Anesthesiology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-449022
American Medical Association (AMA)
Helmi, Mochamat& Uyun, Yusmein& Suwondo, Bambang S.& Widodo, Untung. Comparison of Intrathecal Use of Isobaric and Hyperbaric Bupivacaine during Lower Abdomen Surgery. Journal of Anesthesiology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-449022
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-449022