Role of SPECT and SPECTCT in the Surgical Treatment of Primary Hyperparathyroidism

Abstract EN

Primary hyperparathyroidism is the most common cause of hypercalcemia in the outpatient population.

This condition is usually the result of a single hyperfunctioning parathyroid gland.

Targeted parathyroidectomy guided by intraoperative parathyroid hormone monitoring (IPM) through a small cervical incision has replaced traditional bilateral neck exploration (BNE) as the initial approach in the surgical treatment of primary hyperparathyroidism at many medical centers worldwide.

Preoperative sestamibi-technetium 99m scintigraphy serves as an important prerequisite for successful targeted parathyroidectomy.

Single-photon emission computed tomography (SPECT) and CT fusion, however, is a recent imaging technique that provides a three-dimensional functional image with advanced contrast resolution to greatly improve preoperative localization of parathyroid tumors.