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Viral Vaccines and CTL Response
Joint Authors
Woolard, Stacie N.
Kumaraguru, Uday
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-03-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Immune induction by successful vaccine formulations seems to involve stimulation of both humoral and cellular arms of immunity.
Nevertheless, CD8+ CTLs are of critical relevance in the context of intracellular infection and tumor for many reasons.
The task of exerting antipathogen activity by CD8+ T cells, which principally function to control and eradicate intracellular pathogens, is enabled by constitutive expression of MHC class-I molecules on all tissue types.
CTL induction offers hope for vaccines against pathogens that are resistant to neutralizing activity.
This review discusses the mechanism of immune induction by some successful vaccines and based on the accrued evidence suggests ideas for improved design of CTL-inducing vaccines.
American Psychological Association (APA)
Woolard, Stacie N.& Kumaraguru, Uday. 2010. Viral Vaccines and CTL Response. Journal of Biomedicine and Biotechnology،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-449045
Modern Language Association (MLA)
Woolard, Stacie N.& Kumaraguru, Uday. Viral Vaccines and CTL Response. Journal of Biomedicine and Biotechnology No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-449045
American Medical Association (AMA)
Woolard, Stacie N.& Kumaraguru, Uday. Viral Vaccines and CTL Response. Journal of Biomedicine and Biotechnology. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-449045
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-449045