So Many Plasminogen Receptors : Why?

Joint Authors

Das, Riku
Doeuvre, Loic
Plow, Edward F.

Source

Journal of Biomedicine and Biotechnology

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2012-10-14

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Medicine

Abstract EN

Plasminogen and plasmin tether to cell surfaces through ubiquitously expressed and structurally quite dissimilar family of proteins, as well as some nonproteins, that are collectively referred to as plasminogen receptors.

Of the more than one dozen plasminogen receptors that have been identified, many have been shown to facilitate plasminogen activation to plasmin and to protect bound plasmin from inactivation by inhibitors.

The generation of such localized and sustained protease activity is utilized to facilitate numerous cellular responses, including responses that depend on cellular migration.

However, many cells express multiple plasminogen receptors and numerous plasminogen receptors are expressed on many different cell types.

Furthermore, several different plasminogen receptors can be used to support the same cellular response, such as inflammatory cell migration.

Here, we discuss the perplexing issue: why are there so many different Plg-Rs?

American Psychological Association (APA)

Plow, Edward F.& Doeuvre, Loic& Das, Riku. 2012. So Many Plasminogen Receptors : Why?. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-449054

Modern Language Association (MLA)

Plow, Edward F.…[et al.]. So Many Plasminogen Receptors : Why?. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-449054

American Medical Association (AMA)

Plow, Edward F.& Doeuvre, Loic& Das, Riku. So Many Plasminogen Receptors : Why?. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-449054

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-449054