Hepatoprotective Activity of Dried- and Fermented-Processed Virgin Coconut Oil
Joint Authors
Teh, L. K.
Zakaria, Zainul Amiruddin
Ahmad, Zuraini
Long, K.
Salleh, M. Z.
Rofiee, M. S.
Sulaiman, Mohd Roslan
Somchit, M. N.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-01-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The present study aims to determine the hepatoprotective effect of MARDI-produced virgin coconut oils, prepared by dried- or fermented-processed methods, using the paracetamol-induced liver damage in rats.
Liver injury induced by 3 g/kg paracetamol increased the liver weight per 100 g bodyweight indicating liver damage.
Histological observation also confirms liver damage indicated by the presence of inflammations and necrosis on the respective liver section.
Interestingly, pretreatment of the rats with 10, but not 1 and 5, mL/kg of both VCOs significantly (P<.05) reduced the liver damage caused by the administration of paracetamol, which is further confirmed by the histological findings.
In conclusion, VCO possessed hepatoprotective effect that requires further in-depth study.
American Psychological Association (APA)
Zakaria, Zainul Amiruddin& Rofiee, M. S.& Somchit, M. N.& Ahmad, Zuraini& Sulaiman, Mohd Roslan& Teh, L. K.…[et al.]. 2011. Hepatoprotective Activity of Dried- and Fermented-Processed Virgin Coconut Oil. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-449134
Modern Language Association (MLA)
Zakaria, Zainul Amiruddin…[et al.]. Hepatoprotective Activity of Dried- and Fermented-Processed Virgin Coconut Oil. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-449134
American Medical Association (AMA)
Zakaria, Zainul Amiruddin& Rofiee, M. S.& Somchit, M. N.& Ahmad, Zuraini& Sulaiman, Mohd Roslan& Teh, L. K.…[et al.]. Hepatoprotective Activity of Dried- and Fermented-Processed Virgin Coconut Oil. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-449134
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-449134
