A Computer Model for the Simulation of Nonspherical Particle Dynamics in the Human Respiratory Tract
Author
Source
Physics Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-02
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
In the study presented here deposition of spheres and nonspherical particles with various aspect ratios (0.01–100) in the human respiratory tract was theoretically modeled.
Shape of the nonspherical particles was considered by the application of the latest aerodynamic diameter concepts.
Particle deposition was predicted by using a stochastic model of the lung geometry and simulating particle transport trajectories according to the random-walk algorithm.
Concerning fibers total deposition is significantly enhanced with respect to that of spheres for μm-sized particles, whereby at normal breathing conditions peripheral lung compartments serve as primary deposition targets.
In the case of oblate disks, total deposition becomes mostly remarkable for submicron particles, with the bronchioli and alveoli being targeted to a high extent.
Enhancement of the aerodynamic diameter and/or flow rate generally causes a displacement of deposition maxima from peripheral to more proximal lung regions.
From these findings, it can be concluded that these particle classes may represent tremendous occupational hazards, especially if they are attached with radioactive elements or heavy metals.
American Psychological Association (APA)
Sturm, Robert. 2012. A Computer Model for the Simulation of Nonspherical Particle Dynamics in the Human Respiratory Tract. Physics Research International،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-449139
Modern Language Association (MLA)
Sturm, Robert. A Computer Model for the Simulation of Nonspherical Particle Dynamics in the Human Respiratory Tract. Physics Research International No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-449139
American Medical Association (AMA)
Sturm, Robert. A Computer Model for the Simulation of Nonspherical Particle Dynamics in the Human Respiratory Tract. Physics Research International. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-449139
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-449139