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Utility of Serum Neopterin and Serum IL-2 Receptor Levels to Predict Absolute CD4 T Lymphocyte Count in HIV Infected Cases
Joint Authors
Gautam, Hitender
Bhalla, Preena
Anuradha, S.
Chakravarti, Anita
Saini, Sanjeev
Dewan, Richa
Chadha, Sanjim
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-05
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
A prospective study was carried out to evaluate the efficacy of serum neopterin and soluble IL-2 receptor (sIL-2R) concentrations in comparison to CD4 count to study the progression of HIV disease and monitor response to ART in HIV cases.
One hundred newly diagnosed HIV seropositive subjects were recruited.
CD4 counts were determined by FACS system.
Serum neopterin and sIL-2R levels were measured using enzyme immunoassay.
In our study, levels of neopterin and sIL-2R were significantly higher in subjects with CD4 <200 cells/μL (with S.
neopterin levels of >25.1 nmol/L and sIL-2R levels of >47.1 pM as cutoff values for CD4 <200 cells/μL) compared to those in subjects with CD4 >200 cells/μL at baseline which indicate that these markers can be utilized for initiation of ART in HIV cases.
The levels of these markers decreased significantly after initiation of ART.
In patients with CD4 >200 cells/μL, these markers are helpful in predicting disease progression.
American Psychological Association (APA)
Chadha, Sanjim& Bhalla, Preena& Gautam, Hitender& Chakravarti, Anita& Saini, Sanjeev& Anuradha, S.…[et al.]. 2013. Utility of Serum Neopterin and Serum IL-2 Receptor Levels to Predict Absolute CD4 T Lymphocyte Count in HIV Infected Cases. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-449224
Modern Language Association (MLA)
Chadha, Sanjim…[et al.]. Utility of Serum Neopterin and Serum IL-2 Receptor Levels to Predict Absolute CD4 T Lymphocyte Count in HIV Infected Cases. Interdisciplinary Perspectives on Infectious Diseases No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-449224
American Medical Association (AMA)
Chadha, Sanjim& Bhalla, Preena& Gautam, Hitender& Chakravarti, Anita& Saini, Sanjeev& Anuradha, S.…[et al.]. Utility of Serum Neopterin and Serum IL-2 Receptor Levels to Predict Absolute CD4 T Lymphocyte Count in HIV Infected Cases. Interdisciplinary Perspectives on Infectious Diseases. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-449224
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-449224