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The Effect of Mycobacterium avium Complex Infections on Routine Mycobacterium bovis Diagnostic Tests
Joint Authors
Corbett, David
McNair, Jim
Strain, Sam
Bakker, Douwe
Andersen, Peter L.
Barry, Claire
Source
Veterinary Medicine International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Bovine tuberculosis (bTB) is diagnosed in naturally infected populations exposed to a wide variety of other pathogens.
This study describes the cell-mediated immune responses of cattle exposed to Mycobacterium avium subspecies paratuberculosis (Map) and Mycobacterium avium subspecies avium with particular reference to routine antefmortem Mycobacterium bovis diagnostic tests.
The IFN-γ released in response to stimulated blood was found to peak later in the Map-exposed group and was more sustained when compared to the Maa-exposed group.
There was a very close correlation between the responses to the purified protein derivatives (PPD) used for stimulation (PPDa, PPDb, and PPDj) with PPDa and PPDj most closely correlated.
On occasion, in the Map-infected cattle, PPDb-biased responses were seen compared to PPDa suggesting that some Map-infected cattle could be misclassified as M.
bovis infected using this test with these reagents.
This bias was not seen when PPDj was used.
SICCT results were consistent with the respective infections and all calves would have been classed skin test negative.
American Psychological Association (APA)
Barry, Claire& Corbett, David& Bakker, Douwe& Andersen, Peter L.& McNair, Jim& Strain, Sam. 2011. The Effect of Mycobacterium avium Complex Infections on Routine Mycobacterium bovis Diagnostic Tests. Veterinary Medicine International،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-449274
Modern Language Association (MLA)
Barry, Claire…[et al.]. The Effect of Mycobacterium avium Complex Infections on Routine Mycobacterium bovis Diagnostic Tests. Veterinary Medicine International No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-449274
American Medical Association (AMA)
Barry, Claire& Corbett, David& Bakker, Douwe& Andersen, Peter L.& McNair, Jim& Strain, Sam. The Effect of Mycobacterium avium Complex Infections on Routine Mycobacterium bovis Diagnostic Tests. Veterinary Medicine International. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-449274
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-449274