Development and Characterization of Novel Porous 3D Alginate-Cockle Shell Powder Nanobiocomposite Bone Scaffold
Joint Authors
Hamid, Muhajir
Yusof, Loqman Mohamed
Perimal, Enoch Kumar
Bharatham, B. Hemabarathy
Abu Bakar, Md. Zuki
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-07
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
A novel porous three-dimensional bone scaffold was developed using a natural polymer (alginate/Alg) in combination with a naturally obtained biomineral (nano cockle shell powder/nCP) through lyophilization techniques.
The scaffold was developed in varying composition mixture of Alg-nCP and characterized using various evaluation techniques as well as preliminary in vitro studies on MG63 human osteoblast cells.
Morphological observations using SEM revealed variations in structures with the use of different Alg-nCP composition ratios.
All the developed scaffolds showed a porous structure with pore sizes ideal for facilitating new bone growth; however, not all combination mixtures showed subsequent favorable characteristics to be used for biological applications.
Scaffolds produced using the combination mixture of 40% Alg and 60% nCP produced significantly promising results in terms of mechanical strength, degradation rate, and increased cell proliferation rates making it potentially the optimum composition mixture of Alg-nCP with future application prospects.
American Psychological Association (APA)
Bharatham, B. Hemabarathy& Abu Bakar, Md. Zuki& Perimal, Enoch Kumar& Yusof, Loqman Mohamed& Hamid, Muhajir. 2014. Development and Characterization of Novel Porous 3D Alginate-Cockle Shell Powder Nanobiocomposite Bone Scaffold. BioMed Research International،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-449430
Modern Language Association (MLA)
Bharatham, B. Hemabarathy…[et al.]. Development and Characterization of Novel Porous 3D Alginate-Cockle Shell Powder Nanobiocomposite Bone Scaffold. BioMed Research International No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-449430
American Medical Association (AMA)
Bharatham, B. Hemabarathy& Abu Bakar, Md. Zuki& Perimal, Enoch Kumar& Yusof, Loqman Mohamed& Hamid, Muhajir. Development and Characterization of Novel Porous 3D Alginate-Cockle Shell Powder Nanobiocomposite Bone Scaffold. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-449430
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-449430