Vitamin C-Induced Oxalate Nephropathy
Joint Authors
Lamarche, Jorge
Peguero, Alfredo
Nair, Reji
Courville, Craig
Source
International Journal of Nephrology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-16
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Although a multitude of syndromes have been thoroughly described as a result of vitamin deficiencies, over consumption of such substances may also be quite dangerous.
Intratubular crystallization of calcium oxalate as a result of hyperoxaluria can cause acute renal failure.
This type of renal failure is known as oxalate nephropathy.
Hyperoxaluria occurs as a result of inherited enzymatic deficiencies known as primary hyperoxaluria or from exogenous sources known as secondary hyperoxaluria.
Extensive literature has reported and explained the mechanism of increased absorption of oxalate in malabsorptive syndromes leading to renal injury.
However, other causes of secondary hyperoxaluria may also take place either via direct dietary consumption of oxalate rich products or via other substances which may metabolize into oxalate within the body.
Vitamin C is metabolized to oxalate.
Oral or parenteral administration of this vitamin has been used in multiple settings such as an alternative treatment of malignancy or as an immune booster.
This article presents a clinical case in which ingestion of high amounts of vitamin C lead to oxalate nephropathy.
This article further reviews other previously published cases in order to illustrate and highlight the potential renal harm this vitamin poses if consumed in excessive amounts.
American Psychological Association (APA)
Lamarche, Jorge& Nair, Reji& Peguero, Alfredo& Courville, Craig. 2011. Vitamin C-Induced Oxalate Nephropathy. International Journal of Nephrology،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-449458
Modern Language Association (MLA)
Lamarche, Jorge…[et al.]. Vitamin C-Induced Oxalate Nephropathy. International Journal of Nephrology No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-449458
American Medical Association (AMA)
Lamarche, Jorge& Nair, Reji& Peguero, Alfredo& Courville, Craig. Vitamin C-Induced Oxalate Nephropathy. International Journal of Nephrology. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-449458
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-449458