Initial In Vivo Quantification of Tc-99m Sestamibi Uptake as a Function of Tissue Type in Healthy Breasts Using Dedicated Breast SPECT-CT
Joint Authors
Tornai, Martin P.
Perez, Kristy L.
Shah, Jainil P.
McCracken, Emily K. E.
Wong, Terence Z.
Mann, Steve D.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
A pilot study is underway to quantify in vivo the uptake and distribution of Tc-99m Sestamibi in subjects without previous history of breast cancer using a dedicated SPECT-CT breast imaging system.
Subjects undergoing diagnostic parathyroid imaging studies were consented and imaged as part of this IRB-approved breast imaging study.
For each of the seven subjects, one randomly selected breast was imaged prone-pendant using the dedicated, compact breast SPECT-CT system underneath the shielded patient support.
Iteratively reconstructed and attenuation and/or scatter corrected images were coregistered; CT images were segmented into glandular and fatty tissue by three different methods; the average concentration of Sestamibi was determined from the SPECT data using the CT-based segmentation and previously established quantification techniques.
Very minor differences between the segmentation methods were observed, and the results indicate an average image-based in vivo Sestamibi concentration of 0.10±0.16 μCi/mL with no preferential uptake by glandular or fatty tissues.
American Psychological Association (APA)
Mann, Steve D.& Perez, Kristy L.& McCracken, Emily K. E.& Shah, Jainil P.& Wong, Terence Z.& Tornai, Martin P.. 2012. Initial In Vivo Quantification of Tc-99m Sestamibi Uptake as a Function of Tissue Type in Healthy Breasts Using Dedicated Breast SPECT-CT. Journal of Oncology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-449461
Modern Language Association (MLA)
Mann, Steve D.…[et al.]. Initial In Vivo Quantification of Tc-99m Sestamibi Uptake as a Function of Tissue Type in Healthy Breasts Using Dedicated Breast SPECT-CT. Journal of Oncology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-449461
American Medical Association (AMA)
Mann, Steve D.& Perez, Kristy L.& McCracken, Emily K. E.& Shah, Jainil P.& Wong, Terence Z.& Tornai, Martin P.. Initial In Vivo Quantification of Tc-99m Sestamibi Uptake as a Function of Tissue Type in Healthy Breasts Using Dedicated Breast SPECT-CT. Journal of Oncology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-449461
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-449461