Effect of ω-3 Fatty Acid on Gastrointestinal Motility after Abdominal Operation in Rats
Joint Authors
Zhu, Guang-Jin
Yu, Jian-Chun
Kang, Wei-Ming
Zhang, Qun
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-16
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objective.
To investigate whether ω-3 fatty acid could stimulate gastrointestinal motility after abdominal operation.
Method.
Wistar rats were randomly divided into 3 group (normal saline group, intralipid group, and ω-3 fatty acid group, n=18/group) after partial caecectomy and gastrostomosis, each group was divided into 3 groups (POD1, POD3, and POD6, n=6/group).
Serum gastrin (GAS), motilin (MTL), interleukin-1 (IL-1), interleukin-6 (IL-6), tissue necrosis factor-α (TNF-α), cyclooxygenase-2 (COX-2), gastric emptying rate, and small bowel propulsion rate were measured.
Results.
On POD 3, gastric emptying rate and small bowel propulsion rate in ω-3 fatty acid group were higher than those in normal saline group and intralipid group.
Serum GAS and MTL levels in ω-3 fatty acid group were higher than those in normal saline group, but serum IL-1, IL-6, TNF-α, and COX-2 levels were lower than those in normal saline group and intralipid group.
Conclusion.
ω-3 fatty acid could accelerate the recovery of gastrointestinal mobility after abdominal operation in rats, mainly by relieving postoperative inflammation.
American Psychological Association (APA)
Zhang, Qun& Yu, Jian-Chun& Kang, Wei-Ming& Zhu, Guang-Jin. 2011. Effect of ω-3 Fatty Acid on Gastrointestinal Motility after Abdominal Operation in Rats. Mediators of Inflammation،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-449941
Modern Language Association (MLA)
Zhang, Qun…[et al.]. Effect of ω-3 Fatty Acid on Gastrointestinal Motility after Abdominal Operation in Rats. Mediators of Inflammation No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-449941
American Medical Association (AMA)
Zhang, Qun& Yu, Jian-Chun& Kang, Wei-Ming& Zhu, Guang-Jin. Effect of ω-3 Fatty Acid on Gastrointestinal Motility after Abdominal Operation in Rats. Mediators of Inflammation. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-449941
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-449941