Colonic Perforation in a Child with Crohn's Disease : Successful Medical Treatment Rescues from Colectomy
Joint Authors
Gasparetto, Marco
Kleon, Wolfgang
Guariso, Graziella
Giorgi, Benedetta
al-Bunni, Faise
Source
Case Reports in Gastrointestinal Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-29
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
The challenging treatment of penetrating paediatric Crohn’s disease (CD) involves pharmacological and surgical approaches.
Despite a proved efficacy of anti-TNF agents for treatment of complex fistula, a large number of patients cannot achieve a complete healing and relapse during the followup.
Aim.
We report a paediatric case with CD and colonic perforation who was successfully treated with medical therapy only, including anti-TNFα.
Case Presentation.
During a colonoscopy performed on a 9-year-old girl with CD, a perforation occurred in correspondence of a fistula at the colonic splenic flexure.
The formation of a collection was then detected (US, enteric-CT), as well as a fistula connecting the colon to the collection.
The girl was kept fasting and treated with total parenteral nutrition and antibiotic therapy.
Treatment with Infliximab was also started, and after the third dose a US control showed disappearance of the collection and healing of the enteric fistula.
Parenteral nutrition was progressively substituted with enteral feeding, and no surgical treatments were needed.
Discussion.
In pubertal children with penetrating CD, the option of an efficacious medical treatment to avoid a major surgical approach on the bowel is to be aimed for growth improvement.
This approach requires a strictly monitored long-term followup.
American Psychological Association (APA)
Gasparetto, Marco& Giorgi, Benedetta& Kleon, Wolfgang& al-Bunni, Faise& Guariso, Graziella. 2012. Colonic Perforation in a Child with Crohn's Disease : Successful Medical Treatment Rescues from Colectomy. Case Reports in Gastrointestinal Medicine،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-449958
Modern Language Association (MLA)
Gasparetto, Marco…[et al.]. Colonic Perforation in a Child with Crohn's Disease : Successful Medical Treatment Rescues from Colectomy. Case Reports in Gastrointestinal Medicine No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-449958
American Medical Association (AMA)
Gasparetto, Marco& Giorgi, Benedetta& Kleon, Wolfgang& al-Bunni, Faise& Guariso, Graziella. Colonic Perforation in a Child with Crohn's Disease : Successful Medical Treatment Rescues from Colectomy. Case Reports in Gastrointestinal Medicine. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-449958
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-449958