TRIM22 : A Diverse and Dynamic Antiviral Protein
Joint Authors
Barr, Stephen D.
Hattlmann, Clayton J.
Kelly, Jenna N.
Source
Molecular Biology International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-08
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
The tripartite motif (TRIM) family of proteins is an evolutionarily ancient group of proteins with homologues identified in both invertebrate and vertebrate species.
Human TRIM22 is one such protein that has a dynamic evolutionary history that includes gene expansion, gene loss, and strong signatures of positive selection.
To date, TRIM22 has been shown to restrict the replication of a number of viruses, including encephalomyocarditis virus (EMCV), hepatitis B virus (HBV), and human immunodeficiency virus type 1 (HIV-1).
In addition, TRIM22 has also been implicated in cellular differentiation and proliferation and may play a role in certain cancers and autoimmune diseases.
This comprehensive paper summarizes our current understanding of TRIM22 structure and function.
American Psychological Association (APA)
Hattlmann, Clayton J.& Kelly, Jenna N.& Barr, Stephen D.. 2012. TRIM22 : A Diverse and Dynamic Antiviral Protein. Molecular Biology International،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-450054
Modern Language Association (MLA)
Hattlmann, Clayton J.…[et al.]. TRIM22 : A Diverse and Dynamic Antiviral Protein. Molecular Biology International No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-450054
American Medical Association (AMA)
Hattlmann, Clayton J.& Kelly, Jenna N.& Barr, Stephen D.. TRIM22 : A Diverse and Dynamic Antiviral Protein. Molecular Biology International. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-450054
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-450054
