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Can Bone Tissue Engineering Contribute to Therapy Concepts after Resection of Musculoskeletal Sarcoma?
Joint Authors
van Griensven, Martijn
Holzapfel, Boris Michael
Prodinger, Peter Michael
Hutmacher, Dietmar Werner
Chhaya, Mohit Prashant
Holzapfel, Nina Pauline
Rudert, Maximilian
Melchels, Ferry Petrus Wilhelmus
von Eisenhart-Rothe, Ruediger
Schantz, Jan-Thorsten
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-14
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Resection of musculoskeletal sarcoma can result in large bone defects where regeneration is needed in a quantity far beyond the normal potential of self-healing.
In many cases, these defects exhibit a limited intrinsic regenerative potential due to an adjuvant therapeutic regimen, seroma, or infection.
Therefore, reconstruction of these defects is still one of the most demanding procedures in orthopaedic surgery.
The constraints of common treatment strategies have triggered a need for new therapeutic concepts to design and engineer unparalleled structural and functioning bone grafts.
To satisfy the need for long-term repair and good clinical outcome, a paradigm shift is needed from methods to replace tissues with inert medical devices to more biological approaches that focus on the repair and reconstruction of tissue structure and function.
It is within this context that the field of bone tissue engineering can offer solutions to be implemented into surgical therapy concepts after resection of bone and soft tissue sarcoma.
In this paper we will discuss the implementation of tissue engineering concepts into the clinical field of orthopaedic oncology.
American Psychological Association (APA)
Holzapfel, Boris Michael& Chhaya, Mohit Prashant& Melchels, Ferry Petrus Wilhelmus& Holzapfel, Nina Pauline& Prodinger, Peter Michael& von Eisenhart-Rothe, Ruediger…[et al.]. 2013. Can Bone Tissue Engineering Contribute to Therapy Concepts after Resection of Musculoskeletal Sarcoma?. Sarcoma،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-450068
Modern Language Association (MLA)
Holzapfel, Boris Michael…[et al.]. Can Bone Tissue Engineering Contribute to Therapy Concepts after Resection of Musculoskeletal Sarcoma?. Sarcoma No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-450068
American Medical Association (AMA)
Holzapfel, Boris Michael& Chhaya, Mohit Prashant& Melchels, Ferry Petrus Wilhelmus& Holzapfel, Nina Pauline& Prodinger, Peter Michael& von Eisenhart-Rothe, Ruediger…[et al.]. Can Bone Tissue Engineering Contribute to Therapy Concepts after Resection of Musculoskeletal Sarcoma?. Sarcoma. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-450068
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-450068