Human Schistosome Infection and Allergic Sensitisation
Joint Authors
Rujeni, Nadine
Mutapi, Francisca
Taylor, David W.
Source
Journal of Parasitology Research
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-27
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Several field studies have reported an inverse relationship between the prevalence of helminth infections and that of allergic sensitisation/atopy.
Recent studies show that immune responses induced by helminth parasites are, to an extent, comparable to allergic sensitisation.
However, helminth products induce regulatory responses capable of inhibiting not only antiparasite immune responses, but also allergic sensitisation.
The relative effects of this immunomodulation on the development of protective schistosome-specific responses in humans has yet to be demonstrated at population level, and the clinical significance of immunomodulation of allergic disease is still controversial.
Nonetheless, similarities in immune responses against helminths and allergens pose interesting mechanistic and evolutionary questions.
This paper examines the epidemiology, biology and immunology of allergic sensitisation/atopy, and schistosome infection in human populations.
American Psychological Association (APA)
Rujeni, Nadine& Taylor, David W.& Mutapi, Francisca. 2012. Human Schistosome Infection and Allergic Sensitisation. Journal of Parasitology Research،Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-450187
Modern Language Association (MLA)
Rujeni, Nadine…[et al.]. Human Schistosome Infection and Allergic Sensitisation. Journal of Parasitology Research No. 2012 (2012), pp.1-17.
https://search.emarefa.net/detail/BIM-450187
American Medical Association (AMA)
Rujeni, Nadine& Taylor, David W.& Mutapi, Francisca. Human Schistosome Infection and Allergic Sensitisation. Journal of Parasitology Research. 2012. Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-450187
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-450187