The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1Th2 Imbalance and Inflammation

Joint Authors

Kvalheim, Gunnar
Lyberg, Torstein
Johnson, Egil
Hetland, Geir

Source

Advances in Pharmacological Sciences

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-09-06

Country of Publication

Egypt

No. of Pages

10

Main Subjects

Pharmacology

Abstract EN

The medicinal mushroom Agaricus blazei Murill from the Brazilian rain forest has been used in traditional medicine and as health food for the prevention of a range of diseases, including infection, allergy, and cancer.

Other scientists and we have examined whether there is scientific evidence behind such postulations.

Agaricus blazei M is rich in the immunomodulating polysaccharides, β-glucans, and has been shown to have antitumor, anti-infection, and antiallergic/-asthmatic properties in mouse models, in addition to anti-inflammatory effects in inflammatory bowel disease patients.

These effects are mediated through the mushroom's stimulation of innate immune cells, such as monocytes, NK cells, and dendritic cells, and the amelioration of a skewed Th1/Th2 balance and inflammation.

American Psychological Association (APA)

Hetland, Geir& Johnson, Egil& Lyberg, Torstein& Kvalheim, Gunnar. 2011. The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1Th2 Imbalance and Inflammation. Advances in Pharmacological Sciences،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-450332

Modern Language Association (MLA)

Hetland, Geir…[et al.]. The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1Th2 Imbalance and Inflammation. Advances in Pharmacological Sciences No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-450332

American Medical Association (AMA)

Hetland, Geir& Johnson, Egil& Lyberg, Torstein& Kvalheim, Gunnar. The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1Th2 Imbalance and Inflammation. Advances in Pharmacological Sciences. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-450332

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-450332