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Genital HSV Detection among HIV-1-Infected Pregnant Women in Labor
Joint Authors
Watts, D. Heather
Hitti, Jane
Huang, Meei-Li
Wald, Anna
Selke, Stacy
Brown, Zane
Patterson, Janna
Corey, Lawrence
Source
Infectious Diseases in Obstetrics and Gynecology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-27
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objective.
To compare genital HSV shedding among HIV-positive and HIV-negative women.
Methods.
Women with and without known HIV infection who delivered at the University of Washington Medical Center between 1989–1996 had HSV serologies done as part of clinical care.
Genital swabs from HSV-2-seropositive women were evaluated by real-time quantitative HSV DNA PCR.
Results.
HSV-2 seroprevalence was 71% and 30% among 75 HIV-positive and 3051 HIV-negative women, respectively, (P<.001).
HSV was detected at delivery in the genital tract of 30.8% of HIV-seropositive versus 9.5% of HIV-negative women (RR=3.2, 95% CI 1.6 to 6.5, P=.001).
The number of virion copies shed per mL was similar (log 3.54 for HIV positive versus 3.90 for HIV negative, P=.99).
Conclusions.
Our study demonstrated that HIV-, HSV-2-coinfected women are more likely to shed HSV at delivery.
American Psychological Association (APA)
Patterson, Janna& Hitti, Jane& Selke, Stacy& Huang, Meei-Li& Watts, D. Heather& Brown, Zane…[et al.]. 2011. Genital HSV Detection among HIV-1-Infected Pregnant Women in Labor. Infectious Diseases in Obstetrics and Gynecology،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-450408
Modern Language Association (MLA)
Patterson, Janna…[et al.]. Genital HSV Detection among HIV-1-Infected Pregnant Women in Labor. Infectious Diseases in Obstetrics and Gynecology No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-450408
American Medical Association (AMA)
Patterson, Janna& Hitti, Jane& Selke, Stacy& Huang, Meei-Li& Watts, D. Heather& Brown, Zane…[et al.]. Genital HSV Detection among HIV-1-Infected Pregnant Women in Labor. Infectious Diseases in Obstetrics and Gynecology. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-450408
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-450408