PHBVPAM Scaffolds with Local Oriented Structure through UV Polymerization for Tissue Engineering
Joint Authors
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-22
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Locally oriented tissue engineering scaffolds can provoke cellular orientation and direct cell spread and migration, offering an exciting potential way for the regeneration of the complex tissue.
Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) scaffolds with locally oriented hydrophilic polyacrylamide (PAM) inside the macropores of the scaffolds were achieved through UV graft polymerization.
The interpenetrating PAM chains enabled good interconnectivity of PHBV/PAM scaffolds that presented a lower porosity and minor diameter of pores than PHBV scaffolds.
The pores with diameter below 100 μm increased to 82.15% of PHBV/PAM scaffolds compared with 31.5% of PHBV scaffolds.
PHBV/PAM scaffold showed a much higher compressive elastic modulus than PHBV scaffold due to PAM stuffing.
At 5 days of culturing, sheep chondrocytes spread along the similar direction in the macropores of PHBV/PAM scaffolds.
The locally oriented PAM chains might guide the attachment and spreading of chondrocytes and direct the formation of microfilaments via contact guidance.
American Psychological Association (APA)
Ke, Yu& Wu, Gang& Wang, Yingjun. 2014. PHBVPAM Scaffolds with Local Oriented Structure through UV Polymerization for Tissue Engineering. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-450433
Modern Language Association (MLA)
Ke, Yu…[et al.]. PHBVPAM Scaffolds with Local Oriented Structure through UV Polymerization for Tissue Engineering. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-450433
American Medical Association (AMA)
Ke, Yu& Wu, Gang& Wang, Yingjun. PHBVPAM Scaffolds with Local Oriented Structure through UV Polymerization for Tissue Engineering. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-450433
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-450433