Ten-Year Survival in 75-Year-Old Men and Women : Predictive Ability of Total Cholesterol, HDL-C, and LDL-C
Joint Authors
Hedberg, Pär
Lönnberg, Ingemar
Öhrvik, John
Nilsson, Göran
Source
Current Gerontology and Geriatrics Research
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-04-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
The purpose of this study was to investigate prognostic impact of cholesterol and its subfractions among 75-year-old people from the general population.
Methods and Results.
The study comprised a random sample (222 women and 210 men) from the general population (participation rate 70%).
During 10-year follow-up, 19% of women and 35% of men experienced a major cardiovascular event (MCVE).
The all-cause mortality was 29% for women and 47% for men.
After adjustment for cardiovascular risk factors, a low level of high-density lipoprotein cholesterol (HDL-C) was significantly associated with MCVE (P=.006) and mortality (P=.011) in men but not in women.
The prognostic sex disparity was nearly significant (P=.051 for MCVE and .067 for mortality).
The associations of adjusted HDL-C to MCVE and mortality were unchanged after excluding individuals with prevalent stroke or MI.
Total cholesterol and low-density lipoprotein cholesterol (LDL-C) were not significantly related to prognosis in either sex.
Main Conclusions.
HDL-C was associated with dismal prognosis in men but not in women.
Elderly men with HDL-C <40 mg/dL deserve particular attention for cardiovascular prevention.
American Psychological Association (APA)
Nilsson, Göran& Öhrvik, John& Lönnberg, Ingemar& Hedberg, Pär. 2009. Ten-Year Survival in 75-Year-Old Men and Women : Predictive Ability of Total Cholesterol, HDL-C, and LDL-C. Current Gerontology and Geriatrics Research،Vol. 2009, no. 2009, pp.1-7.
https://search.emarefa.net/detail/BIM-450473
Modern Language Association (MLA)
Nilsson, Göran…[et al.]. Ten-Year Survival in 75-Year-Old Men and Women : Predictive Ability of Total Cholesterol, HDL-C, and LDL-C. Current Gerontology and Geriatrics Research No. 2009 (2009), pp.1-7.
https://search.emarefa.net/detail/BIM-450473
American Medical Association (AMA)
Nilsson, Göran& Öhrvik, John& Lönnberg, Ingemar& Hedberg, Pär. Ten-Year Survival in 75-Year-Old Men and Women : Predictive Ability of Total Cholesterol, HDL-C, and LDL-C. Current Gerontology and Geriatrics Research. 2009. Vol. 2009, no. 2009, pp.1-7.
https://search.emarefa.net/detail/BIM-450473
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-450473