Effectiveness of Keishibukuryogan on Chronic-Stage Lichenification Associated with Atopic Dermatitis
Joint Authors
Furuichi, Megumi
Shimizu, Tadamichi
Shimada, Yutaka
Hikiami, Hiroaki
Makino, Teruhiko
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-14
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Atopic dermatitis (AD) is a common inflammatory skin disease with recurring episodes of itching and a chronic relapsing course.
Keishibukuryogan (KBG) is a traditional herbal medicine, composed of five kinds of medical plants and has been administered to patients with blood stagnation in Japan.
This study investigated the effect of KBG on the disease activity in AD (n=45) patients.
AD patients were administered KBG for 4 to 6 weeks in addition to their prescribed medications.
The results showed that the SCORAD index and VAS score were significantly decreased after the administration of KBG (P<0.01).
KBG also decreased the serum LDH level significantly (P<0.01).
The global assessment of the clinical response in SCORAD index showed that 88.5% of the patients with moderate improvement to excellent response (n=26) had a high lichenification score (lichenification score ≥2 in SCORAD).
On the other hand, only 42.1% of the patients with no improvement to mild improvement (n=19) had a high lichenification score.
Furthermore, long-term administration of KBG for 9–67 weeks showed a marked improvement in patients with a high lichenification score.
Therefore, KBG was found to be effective against AD, particularly in cases presenting with lichenified lesions.
American Psychological Association (APA)
Furuichi, Megumi& Makino, Teruhiko& Hikiami, Hiroaki& Shimada, Yutaka& Shimizu, Tadamichi. 2012. Effectiveness of Keishibukuryogan on Chronic-Stage Lichenification Associated with Atopic Dermatitis. ISRN Dermatology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-450497
Modern Language Association (MLA)
Furuichi, Megumi…[et al.]. Effectiveness of Keishibukuryogan on Chronic-Stage Lichenification Associated with Atopic Dermatitis. ISRN Dermatology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-450497
American Medical Association (AMA)
Furuichi, Megumi& Makino, Teruhiko& Hikiami, Hiroaki& Shimada, Yutaka& Shimizu, Tadamichi. Effectiveness of Keishibukuryogan on Chronic-Stage Lichenification Associated with Atopic Dermatitis. ISRN Dermatology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-450497
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-450497